Intensive amount of published data regarding TBS predictability of fracture has led the Sheffield University FRAX™ Group to explore TBS interaction with FRAX™ in order to provide a new model for TBS clinical application. Observations from the FRAX™ Group are the following – based on TBS literature review and on population-based meta-analysis study1 :

  1. TBS significantly and consistently predicts:
    • vertebral and non-vertebral fracture;
    • death;
  2. These observations are valid in both women and men;
  3. Thus, independently from:
    • BMD;
    • Clinical risk factors;
    • FRAX™.

FRAX™ Group concluded that TBS can be used in risk assessment and help improve the prediction of risk of fracture and risk of death. This raises the question of the clinical application of TBS and how to easily integrate it into the existing osteoporosis management workflow. Visit the other pages about FRAX™ Adjusted for TBS to know more about the model and its clinical use. To calculate your FRAX™ Adjusted for TBS now, visit Sheffield website: https://www.shef.ac.uk/FRAX/tool.jsp

To read the News Stories about FRAX Adjusted for TBS from the latest IOF Newsletter – Bone Blast – issued 2015 May, 6th, click here: “FRAX fracture risk assessment tool output can now be modified by TBS” 


1A meta-analysis of trabecular bone score in fracture risk prediction and its interaction with FRAX, J. A. Kanis, Oral presentation, WCO-IOF-ESCEO 2015, Milan.