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Authors

Bandirali, Michele; Di Leo, Giovanni; Messina, Carmelo; Pastor Lopez, Maria Juana; Mai, Alessandro; Ulivieri, Fabio M.; Sardanelli, Francesco

Publication Year

2015

Abstract Note

OBJECTIVE: The trabecular bone score (TBS) accounts for the bone microarchitecture and is calculated on dual-energy X-ray absorptiometry (DXA). We estimated the reproducibility of the TBS using different scan modes compared to the reproducibility bone mineral density (BMD). MATERIALS AND METHODS: A spine phantom was used with a Hologic QDR-Discovery A densitometer. For each scan mode [fast array, array, high definition (HD)], 25 scans were automatically performed without phantom repositioning, a further 25 scans were performed with phantom repositioning. For each scan, the TBS was obtained. The coefficient of variation (CoV) was calculated as the ratio between standard deviation and mean, percent least significant change (LSC%) as 2.8 × CoV, reproducibility as the complement to 100 % of LSC%. Differences among scan modes were assessed using ANOVA. RESULTS: Without phantom repositioning, the mean TBS (mm(-1)) was: 1.352 (fast array), 1.321 (array), and 1.360 (HD), with phantom repositioning, it was 1.345, 1.332, and 1.362, respectively. Reproducibility of the TBS without phantom repositioning was 97.7 % (fast array), 98.3 % (array), and 98.2 % (HD), with phantom repositioning, it was 97.9 %, 98.7 %, and 98.4 %, respectively. LSC% was ≤ 2.26 %. Differences among scan modes were all statistically significant (p ≤ 0.019). Reproducibility of BMD was 99.1 % with all scan modes, while LSC% was from 0.86 % to 0.91 %. CONCLUSION: Reproducibility error of the TBS was 2-3-fold higher than that of BMD. Although statistically significant, differences in TBS among scan modes were within the highest LSC%. Thus, the three scan modes can be considered interchangeable.

Journal

Skeletal Radiology

Volume

44

Pages

573-576

Tags

Hologic     Italy     Phantom     Technical variability    
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