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Authors

Iki, M.; Fujita, Y.; Tamaki, J.; Kouda, K.; Yura, A.; Sato, Y.; Moon, J.-S.; Winzenrieth, R.; Okamoto, N.; Kurumatani, N.

Publication Year

2015

Abstract Note

UNLABELLED: FRAX(R) is widely used to evaluate fracture risk of individuals in clinical settings. However, FRAX(R) prediction accuracy is not sufficient, and improvement is desired. Trabecular bone score, a bone microarchitecture index, may improve FRAX(R) prediction accuracy for major osteoporotic fractures in community-dwelling elderly Japanese men. INTRODUCTION: To improve fracture risk assessment in clinical settings, we evaluated whether the combination of FRAX(R) and Trabecular Bone Score (TBS) improves the prediction accuracy of major osteoporotic fractures (MOFs) in elderly Japanese men compared to FRAX(R) alone. METHODS: Two thousand and twelve community-dwelling men aged >/=65 years completed the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Baseline Study comprising lumbar spine (LS) and femoral neck areal bone mineral density (aBMD) measurements, and interviews regarding clinical risk factors required to estimate

Journal

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Volume

26

Pages

1841-1848

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