Authors
Majumdar, Sharmila; Keavney, Tony M.; Rio, Luis Del; Semler, Oliver; Winzenrieth, Renaud
Publication Year
2016
Abstract Note
The aim of this chapter is to introduce promising new tools for the pediatric field able to assess bone microarchitectural structure and texture at the central and axial skeleton using Magnetic Resonance Imaging (MRI), Finite Element Analysis from computed tomography scans or Trabecular Bone Score (TBS) from Dual Energy X-Ray Absorptiometry (DXA) scans. Although all three of these technologies have been used more widely in adults, the promise of enhanced information and improved predictability of fracture offer complementary value to the areal Bone Mineral Density (aBMD) for the diagnosis of skeletal implications of multiple pathological conditions that may affect the skeletal development during growth. This chapter includes a description of each technology and mathematical framework as well as its clinical use in adults and potential applications and limitations for pediatric patients.
Journal
Bone Health Assessment in Pediatrics
Volume
Pages
285-313
Pubmed Link