Authors
Muschitz, Christian; Kautzky-Willer, Alexandra; Rauner, Martina; Winhöfer-Stöckl, Yvonne; Haschka, Judith
Publication Year
2019
Abstract Note
SummaryFragility fractures are increasingly recognized as a complication of both type 1 and type 2 diabetes, with fracture risk that increases with disease duration and poor glycemic control. The identification and management of fracture risk in these patients remains challenging. This manuscript explores the clinical characteristics of bone fragility in adults with diabetes and highlights recent studies that have evaluated areal bone mineral density (BMD), bone microstructure and material properties, biochemical markers, and fracture prediction algorithms (FRAX) in these patients. It further reviews the impact of diabetes drugs on bone tissue as well as the efficacy of osteoporosis treatments in this population. An algorithm for the identification and management of diabetic patients at increased fracture risk is proposed.
Journal
Wiener klinische Wochenschrift
Volume
Pages
Pubmed Link