Authors
Botella Martínez, Sonsoles; Varo Cenarruzabeitia, Nerea; Escalada San Martin, Javier; Calleja Canelas, Amparo
Publication Year
2016
Abstract Note
Type 2 diabetes mellitus prevalence and morbidity are increasing. Osteoporotic fractures are among the 'non-classical' complications of diabetes and been overlooked for a long time, maybe because of their complex diagnostic and therapeutic approach. The usual tools for preventing fragility fractures (such as the fracture risk assessment tool and bone densitometry) underestimate risk of fractures in type2 diabetic patients. New techniques, such as trabecular bone score or bone turnover markers, could be useful, but greater scientific evidence is required to recommend their use in clinical practice. The special characteristics of their pathophysiology result in decreased bone remodeling with normal or even increased bone mineral density, but with low quality. These changes lead to the occurrence of osteoporotic fractures without evidence of densitometric changes, which could be called 'the diabetic paradox'.
Journal
Endocrinologia Y Nutricion: Organo De La Sociedad Espanola De Endocrinologia Y Nutricion
Volume
63
Pages
495-501
Pubmed Link